Investments and Business

Bristol Myers Squibb, the global pharmaceutical giant, said on Friday that it would acquire Karuna Therapeutics, which makes drugs to treat schizophrenia and Alzheimer’s, in an all-cash deal valued at $14 billion as it looks to strengthen its pipeline of neuroscience drugs.Bristol Myers said in a statement that it would pay $330 per share in cash, a premium of roughly 53 percent to Karuna’s share price on Thursday.An increasing prevalence of schizophrenia, driven in part by an aging population, has led to a push to make more drugs to treat it. The market for such therapies is estimated to grow…

Seventeen years and more than 1,200 games ago, Andrew Cogliano remembers how difficult it was to traverse the state of California.The Los Angeles Kings, Anaheim Ducks and San Jose Sharks were three of the biggest, heaviest teams in the league. If you had to play all three in succession? Well, good luck. Not only were those teams willing to play a punishing brand of hockey, but they were all highly skilled and generally successful, too.After a few years in Edmonton where he broke into the league, Cogliano was dealt to the Ducks as a free agent in the summer of…

A closely watched measure of inflation cooled notably in November, good news for the Federal Reserve as officials move toward the next phase in their fight against rapid price increases and a positive for the White House as voters see relief from rising costs.The Personal Consumption Expenditures inflation measure, which the Fed cites when it says it aims for 2 percent inflation on average over time, climbed 2.6 percent in the year through November. That was down from 2.9 percent the previous month, and was less than what economists had forecast. Compared with the previous month, prices overall even fell…

It was the depths of the Cold War in the 1960s, and Caracas was on edge.Marxist guerrillas in Venezuela were getting weapons and training from Cuba’s Fidel Castro. Along Venezuela’s eastern border, anticolonial leaders in what was then British Guiana were agitating for independence.Alarmed that a Guyanese leader could create a Cuban beachhead in South America, Venezuela’s staunchly anti-Communist president, Rómulo Betancourt, came up with a strategy, which blunted the independence push: At the United Nations, his government resurrected a long-festering claim to more than half of Guyana’s territory.Now the dispute over Essequibo — an oil-rich, Guyanese region nearly the…

Later in 2020, Ms. Lavelle also complained to the board, describing how she had been traumatized by her daughter’s tongue-tie release.The lactation board, which reports its disciplinary decisions, has not taken action against Ms. Henstrom. A spokeswoman for the board, Susan Brayshaw, declined to comment on the complaints, citing a policy of confidentiality. “Some complaints take significantly longer than others due to the nature of the allegations and related investigations,” she said.Since 2002, the board has revoked the certifications of only three lactation consultants.Ms. Lavelle also filed a complaint against Dr. Zink with the Idaho board of dentistry. The board…

We’re coming down the stretch of the NFL season, and the playoff seedings and Power Rankings are starting to sort themselves out, but that doesn’t mean there haven’t been some surprises along the way. Today, we’re going to look at one surprising aspect of each team’s season.And then we’re going to start looking forward to a No. 1 vs. No. 2 matchup in Week 16 of the season.(Last week: 1)Sunday: Beat Arizona Cardinals 45-29Surprise: Brock PurdyWe’ve let all the talk about whether the second-year quarterback is a top-10 quarterback in the league or even possibly the MVP obscure what remains…

On China’s snowy border with Russia, a dealership that sells trucks has seen its sales double in the past year thanks to Russian customers. China’s exports to its neighbor are so strong that Chinese construction workers built warehouses and 20-story office towers at the border this summer.The border town Heihe is a microcosm of China’s ever closer economic relationship with Russia. China is profiting from Russia’s invasion of Ukraine, which has led Russia to switch from the West to China for purchases of everything from cars to computer chips.Russia, in turn, has sold oil and natural gas to China at…

There was a noticeable absence among the participating countries when Secretary of Defense Lloyd J. Austin III announced that the United States was organizing a new naval task force to confront the threat from Yemen’s Houthi militia marauding against global shipping in the Red Sea.No regional power agreed that its navy would participate. The only Middle Eastern country taking part is the tiny island state of Bahrain, and there was otherwise conspicuous silence from regional capitals.Many Arab countries depend heavily on the trade that flows through the Red Sea, from the Suez Canal in the north to the Bab-al-Mandeb Strait…

Five African countries are battling outbreaks of anthrax, with nearly 1,200 people affected so far and 20 deaths, according to the World Health Organization. But the official tally belies confusion about the exact nature and scale of the outbreaks, which may complicate the efforts needed to contain them.Of the 1,166 presumed anthrax cases in Kenya, Malawi, Uganda, Zambia and Zimbabwe, only 35 have been confirmed with lab tests. That is not unusual or unreasonable, experts said, especially in regions with limited resources.But at least in Uganda, many of the presumed cases have resulted in negative tests for anthrax, raising the…

(Editor’s note: This is excerpted from Mike Sando’s Pick Six of Dec. 18, 2023.)Sean Payton blasting quarterback Russell Wilson on the sideline, then suggesting he was merely upset about officiating, invited all sorts of speculation.It’s hard to fault Payton for losing his cool when officials wiped out a Broncos touchdown with an offensive offside call that seemed indefensible. As one former head coach put it, officials have “lost their minds” searching for penalties associated with Philadelphia’s tush-push plays.It’s just difficult to understand why Payton would funnel any of that rage toward his quarterback.GO DEEPERSean Payton downplays sideline flare up with Russell WilsonThe…